Visceral Adipose Tissue Mobilization
The "Menopause Belly" Shift
Prior to menopause, estrogen directs fat storage to subcutaneous depots (hips and thighs). As estrogen plummets, the body shifts to an androgen-dominant storage pattern, depositing fat deep within the abdomen (Visceral Adipose Tissue or VAT). This is not just cosmetic; VAT is metabolically active tissue that releases inflammatory cytokines.
Mechanism: Catecholamine Resistance
Visceral fat cells have a higher density of Cortisol receptors and Alpha-2 adrenergic receptors (the "anti-burn" receptors). High stress (Cortisol) essentially locks this fat in place. Standard calorie deficits often fail here because the hormonal environment signals "storage mode."
ChemGrade Strategy
Mobilization requires lowering Cortisol first. Protocol: Phosphatidylserine (600mg) to blunt cortisol + Green Tea Extract (EGCG) to inhibit the COMT enzyme, extending the half-life of fat-burning catecholamines.
Clinical Context
This compound is frequently utilized in the Sleep Optimization and Cortisol Management protocols.
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