CHEMGRADE
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WEIGHT-LOSSXX-OPTIMIZATIONMENOPAUSE

Visceral Adipose Tissue Mobilization

2025-03-05//READ: 6 MIN//BY CHEMGRADE RESEARCH

The "Menopause Belly" Shift

Prior to menopause, estrogen directs fat storage to subcutaneous depots (hips and thighs). As estrogen plummets, the body shifts to an androgen-dominant storage pattern, depositing fat deep within the abdomen (Visceral Adipose Tissue or VAT). This is not just cosmetic; VAT is metabolically active tissue that releases inflammatory cytokines.

Mechanism: Catecholamine Resistance

Visceral fat cells have a higher density of Cortisol receptors and Alpha-2 adrenergic receptors (the "anti-burn" receptors). High stress (Cortisol) essentially locks this fat in place. Standard calorie deficits often fail here because the hormonal environment signals "storage mode."

ChemGrade Strategy

Mobilization requires lowering Cortisol first. Protocol: Phosphatidylserine (600mg) to blunt cortisol + Green Tea Extract (EGCG) to inhibit the COMT enzyme, extending the half-life of fat-burning catecholamines.

* This analysis is for educational purposes only. ChemGrade does not provide medical advice.

Clinical Context

This compound is frequently utilized in the Sleep Optimization and Cortisol Management protocols.

View Protocol