AMPK Activation Pathways

The Master Switch

AMPK (Adenosine Monophosphate-Activated Protein Kinase) is your body's energy sensor. When activated (usually by fasting or exercise), it tells cells to stop storing fat and start burning energy. It also triggers Autophagy—the cellular "recycling" process that cleans out damaged proteins.

Fasting Mimetics

Modern life (constant eating) keeps AMPK suppressed and mTOR (growth/aging) elevated. To pulse AMPK without starving, we use "Fasting Mimetics":

• Berberine: The most potent oral mimetic.
• Gynostemma (Jiaogulan): Activates AMPK via different pathways than Berberine.
• Hesperidin: Found in citrus peel, shown to modulate lipid metabolism via AMPK.