Cortisol-Testosterone Ratio Optimization
The Catabolic Seesaw
Testosterone (Anabolic) and Cortisol (Catabolic) exist in an inverse relationship. Chronically elevated cortisol—whether from work stress or overtraining—directly suppresses Gonadotropin-Releasing Hormone (GnRH), shutting down testosterone production at the source. This is known as the "Pregnenolone Steal," where the body prioritizes survival (cortisol) over reproduction (testosterone).
Phosphatidylserine: The Cortisol Blunter
Phosphatidylserine (PS) is a phospholipid component of cell membranes. Clinical trials have demonstrated that 600mg-800mg of PS can blunt the exercise-induced cortisol spike by up to 30% without affecting the testosterone response, effectively optimizing the T:C ratio in favor of anabolism.
Timing is Critical
Post-Workout: 400mg to blunt excessive tissue breakdown.
Pre-Bed: 400mg to lower evening cortisol and facilitate Deep Sleep onset.
Clinical Context
This compound is frequently utilized in the Sleep Optimization and Cortisol Management protocols.
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