Cognitive Output Protocols
Cognitive performance is determined by neurotransmitter availability, cerebral blood flow, and mitochondrial energy output. Each compound targets a different bottleneck.
Mechanism Overview
The primary cognitive bottlenecks are acetylcholine (working memory, focus), dopamine/norepinephrine (motivation, executive function), and ATP availability (sustained output). Effective cognitive compounds address one or more of these without creating dependence.
Recommended Foundation Stack
The ChemGrade cognitive stack: Alpha-GPC (300mg) + L-Theanine (200mg) + Creatine (5g daily). Alpha-GPC provides acetylcholine substrate, Theanine smooths caffeine jitter, Creatine provides phosphocreatine buffer for sustained mental output.
Track: reaction time, working memory scores, focus duration. Subjective: morning motivation quality.
All Protocols — Ranked by Efficacy Score
Frequently Asked Questions
What is the best supplement for focus?
Alpha-GPC is the strongest single compound for acute focus, specifically for tasks requiring working memory. Stack it with L-Theanine and caffeine for maximum effect.
Does Creatine help with brain function?
Yes. The brain uses phosphocreatine as an energy buffer during demanding cognitive tasks. Studies show 5g/day improves working memory, especially in sleep-deprived states.
Is L-Tyrosine a stimulant?
No. L-Tyrosine is a catecholamine precursor — it replenishes dopamine and norepinephrine during high-stress or high-fatigue states. It does not create the spike-and-crash pattern of stimulants.
Other Goal Protocols
* Clinical protocols are for educational purposes only. ChemGrade does not provide medical advice. Consult a physician before beginning any supplementation protocol.