CHEMGRADE
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MINERALSXX-OPTIMIZATIONANEMIA

Iron Bisglycinate Bioavailability

2025-03-04//READ: 5 MIN//BY CHEMGRADE RESEARCH

The "Gut Rot" Problem

Standard iron supplements (Ferrous Sulfate) are notorious for causing nausea, constipation, and oxidative stress in the gut. This leads to poor compliance and failed treatment of anemia. Only about 10-15% of Ferrous Sulfate is actually absorbed.

The Chelate Advantage

Iron Bisglycinate is an iron molecule bound to two glycine amino acids. This "chelate" structure allows the iron to bypass the standard metal transporters (DMT1) that are often blocked by inflammation or dietary inhibitors (like phytates). Instead, it is absorbed intact as an amino acid, resulting in 4x higher bioavailability with near-zero gastrointestinal side effects.

Absorption Rule

Always take Iron with Vitamin C (500mg) to create an acidic environment. NEVER take with coffee, tea, or dairy, as tannins and calcium inhibit absorption by up to 60%.

* This analysis is for educational purposes only. ChemGrade does not provide medical advice.

Clinical Context

This compound is frequently utilized in the Sleep Optimization and Cortisol Management protocols.

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