Magnesium Threonate BBB Permeability

The Blood-Brain Barrier Problem

Magnesium is a critical dampener of neuronal firing. However, most forms (Oxide, Citrate, Glycinate) are primarily absorbed into muscle or bone. They struggle to cross the tight junctions of the Blood-Brain Barrier (BBB), making them less effective for "racing thoughts" or neurological anxiety.

The L-Threonate Carrier

Magnesium L-Threonate is unique. The Threonate metabolite acts as a carrier, actively transporting magnesium ions across the BBB. Studies show it elevates cerebrospinal fluid magnesium levels significantly higher than other forms, directly modulating NMDA receptors to reduce neuronal excitability.