Synthesewege von dermalem Kollagen

Executive Summary

Collagen supplementation is often dismissed as "expensive urine" by skeptics who claim proteins are destroyed in the stomach. This view is outdated. Clinical evidence shows that Hydrolyzed Collagen Peptides survive digestion as di- and tri-peptides, acting as potent signaling molecules for dermal repair.

Mechanism: Fibroblast Activation

Ingested collagen works via "False Signaling." The specific peptides (Proline-Hydroxyproline) detected in the bloodstream mimic the byproducts of tissue breakdown. Fibroblasts (skin cells) interpret this high concentration of debris as a sign of injury, triggering a massive upregulation in endogenous collagen synthesis to "repair" the nonexistent damage.

The Vitamin C Requirement

Collagen synthesis requires the hydroxylation of proline and lysine residues to stabilize the helix structure. This enzymatic process is strictly dependent on Vitamin C (Ascorbic Acid). Without sufficient Vitamin C, the new collagen produced is unstable and weak.