CHEMGRADE
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PERFORMANCEXY-OPTIMIZATIONHYPERTROPHY

Ashwagandha KSM-66 for Hypertrophy

2025-03-01//READ: 5 MIN//BY CHEMGRADE RESEARCH

Beyond Stress Relief

Ashwagandha is primarily marketed as an adaptogen for anxiety, but its application in sports performance is clinically significant. The mechanism is twofold: cortisol suppression (reducing muscle catabolism) and enhanced ATP production capacity.

The Wankhede Study (2015)

In a randomized, double-blind, placebo-controlled study, subjects consuming 600mg of KSM-66 daily for 8 weeks demonstrated significantly greater increases in muscle mass and strength compared to placebo.

  • Bench Press: +46 kg (Treatment) vs. +26 kg (Placebo)
  • Muscle Damage: Significantly lower serum creatine kinase (CK) levels, indicating faster recovery.
  • Testosterone: A secondary increase of ~15% was observed, likely due to cortisol reduction.

ChemGrade Verdict

Ashwagandha is a viable hypertrophy agent, specifically for "high-stress" trainees whose gains are stifled by poor recovery. Use 600mg post-workout.

* This analysis is for educational purposes only. ChemGrade does not provide medical advice.

Clinical Context

This compound is frequently utilized in the Sleep Optimization and Cortisol Management protocols.

View Protocol